how skin cells protect them selves agianst stress
The skin is our largest organ, and, among other things, it provides protection against mechanical impacts. To ensure this protection, skin cells have to be connected to one another especially closely. Exactly how this mechanical stability is provided on the molecular level was unclear for a long time.Researchers in the team led by Prof.
Carsten Grashoff from the Institute of Molecular Cell Biology at the University of Münster and the Max Planck Institute have been collaborating with Ludwig Maximilian University and Stanford University and they are now able to demonstrate how mechanical stress on specialized adhesion points, so-called desmosomes, is processed mechanical stress on specialized adhesion points, so-called desmosomes, is processed. They designed a mini-measuring device, which can determine forces along individual components of the desmosomes. When there is only a low level of mechanical stress, other structures in the cell can carry the burden. But if a high degree of stress occurs, then desmosomes come to the rescue.
Skin and Stem Cell Research Center (SSRC) was established in March 2010 with the support from Tehran University of Medical Sciences. The SSRC is directed by professor Nilforoushzadeh in collaborating closely with an advisory board that is comprised of dermatology faculty and aims to serve as a research and educational center to promote scientific advancement in Iran. .
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